A new study reported in Science Daily concluded that tart cherry decreases joint pain and sore muscles in some breast cancer patients by reducing the musculoskeletal effects of aramatrase inhibitors. These inhibitors are a standard treatment for hormone receptive-positive breast cancer in postmenopausal women and help prevent recurrence by inhibiyting the action of amomatasew that is an enzymew that converts androgens to estrogens. Almopst half of women who use this treatment have joint and muscle pain that can be debilitating and may cause patients to stop treatment.
In the random, double-bind study women were plaqced in a group that received 1 ounce of tart cherry concentrate in 8 ounces of water dailyfor 6 weeks with a group who received a placebo. All had stage 1,2,3 non-metastatic breast cancer. The study continued through May 2016 to August 2018 and 60 patients were enrolled. Patients documented their pain intensity at the start of the study, weekly and at the end of the study. Patients who completed the study reported a 34.7% mean decrease in pain compared to 1.4% in the placebo group. Recearchers say the flavonoids and anthocyanins in the tart cherry have an anti-inflammatory properties that may play a role in reducing the side effects observed. There was a statistical significant difference in the pain levels experienced by patients in the group that received the tart cherry.